Research workbench
Structure of human uracil DNA glycosylase (udg) bound to aurintricarboxylic acid (ata)
Analyse Structure of human uracil DNA glycosylase (udg) bound to aurintricarboxylic… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6VBA
- Type
- protein
- Length
- 223 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Uracil-DNA glycosylase
- EC
- 3.2.2.27
- UniProt
- P13051
- Ligands
- QU4
- Pockets
- 2 · best druggability 0.53
Structure
x-ray diffraction · 1 distinct chain · 39% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Uracil-DNA glycosylase (EC 3.2.2.27) | protein | 223 | 39% helix, 11% strand | P13051 |
Ligands and binding sites
- QU4 · 3,3'-[(3-carboxy-4-oxocyclohexa-2,5-dien-1-ylidene) methylene]bis(6-hydroxybenzoic acid) · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 171 | 0.53 | 0.79 | 36 | QU4 |
| 2 | 66 | 0.37 | 0.77 | 12 | empty |
Compared structures
- 6VBA · Structure of human Uracil DNA Glycosylase (UDG) bound to Aurintricarboxylic acid (ATA) · the same entry in another collection · chain A against A, TM-score 1.00
- P13051 · AlphaFold monomer V2.0 prediction for uracil-DNA glycosylase (P13051) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P13051
- Elsewhere: RCSB PDB 6VBA · PDBe 6VBA · UniProt P13051
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.