Research workbench
Fanconi anemia id complex
Analyse Fanconi anemia id complex in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6VAD
- Type
- protein
- Length
- 2,321 residues
- Chains
- 2
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Fanconi anemia, complementation group I; Fanconi anemia group D2 protein
- UniProt
- B7ZMF2, Q9BXW9
- Pockets
- 20 · best druggability 0.80
Structure
electron microscopy · 2 distinct chains · 68% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Fanconi anemia, complementation group I | protein | 1168 | 68% helix, 1% strand | B7ZMF2 |
| B | Fanconi anemia group D2 protein | protein | 1153 | 68% helix, 2% strand | Q9BXW9 |
Pockets
20 pockets found on a 1 Å grid, 14 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 918 | 0.80 | 0.82 | 97 | empty |
| 2 | 1152 | 0.79 | 0.81 | 107 | empty |
| 3 | 130 | 0.75 | 0.94 | 35 | empty |
| 4 | 71 | 0.74 | 0.97 | 14 | empty |
| 5 | 463 | 0.66 | 0.78 | 43 | empty |
Interfaces
1 interface between chains.
- A–B · 2542 Ų buried · 23 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B7ZMF2
- Every structure of UniProt Q9BXW9
- Elsewhere: RCSB PDB 6VAD · PDBe 6VAD · UniProt B7ZMF2 · UniProt Q9BXW9
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