Research workbench
Mouse PKC C1B and C2 domains
Analyse Mouse PKC C1B and C2 domains in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6UWA
- Type
- protein
- Length
- 187 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Protein kinase C
- EC
- 2.7.11.13
- UniProt
- Q4VA93
- Ligands
- PB, ZN, SO4
- Pockets
- 2 · best druggability 0.30
Structure
x-ray diffraction · 1 distinct chain · 11% helix, 40% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Protein kinase C (EC 2.7.11.13) | protein | 187 | 11% helix, 40% strand | Q4VA93 |
Ligands and binding sites
- PB · Lead (II) ion · metal · 4 copies · chains A
- ZN · Zinc ion · metal · 2 copies · chains A
- SO4 · Sulfate ion · ion · 3 copies · chains A
- CIT · Citric acid · additive · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 68 | 0.30 | 0.74 | 17 | PB, CIT |
| 2 | 62 | 0.29 | 0.74 | 14 | empty |
Compared structures
- 6UWA · Mouse PKC C1B and C2 domains · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q4VA93
- Elsewhere: RCSB PDB 6UWA · PDBe 6UWA · UniProt Q4VA93
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