Research workbench
Design of organo-peptides as bipartite PCSK9 antagonists
Analyse Design of organo-peptides as bipartite PCSK9 antagonists in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6U3I
- Type
- protein
- Length
- 1,028 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q8NBP7, A0A0U5BC76
- Ligands
- PQG, CA
Structure
x-ray diffraction · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 582 | — | Q8NBP7 |
| B | — | protein | 10 | — | — |
| H | — | protein | 222 | — | — |
| L | — | protein | 214 | — | A0A0U5BC76 |
Ligands and binding sites
- PQG · Cis-1-amino-4-phenylcyclohexane-1-carboxylic acid · ligand · chains A, B
- CA · Calcium ion · metal · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6U3I · Design of organo-peptides as bipartite PCSK9 antagonists · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8NBP7
- Every structure of UniProt A0A0U5BC76
- Elsewhere: RCSB PDB 6U3I · PDBe 6U3I · UniProt Q8NBP7 · UniProt A0A0U5BC76
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