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Crystal structure of 1918 NS1-ed W187A in complex with the P85-beta- ISH2 domain of human PI3K

Analyse Crystal structure of 1918 NS1-ed W187A in complex with the P85-beta- ISH2… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
6U28
Type
protein
Length
519 residues
Chains
4
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
Q99AU3, O00459

Structure

x-ray diffraction · 4 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein127—Q99AU3
C—protein129—O00459
B—protein119—Q99AU3
D—protein144—O00459

Compared structures

  • 6U28 · Crystal structure of 1918 NS1-ED W187A in complex with the p85-beta-iSH2 domain of human… · the same entry in another collection · chain A against A, TM-score 1.00
  • O00459 · AlphaFold monomer V2.0 prediction for phosphatidylinositol 3-kinase regulatory subunit… · a predicted model of the same protein · chain C against A, TM-score 0.93

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