Research workbench
Solution structure and 1H, 13C and 15N chemical shift assignments for the complex of VPS29 with varp 687-747
Analyse Solution structure and 1H, 13C and 15N chemical shift assignments for the… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6TL0
- Type
- protein
- Length
- 253 residues
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Vacuolar protein sorting-associated protein 29; Ankyrin repeat domain-containing protein…
- UniProt
- Q9QZ88, Q96NW4
- Ligands
- ZN
- Pockets
- 2 · best druggability 0.35
Structure
solution nmr · 2 distinct chains · 11% helix, 27% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Vacuolar protein sorting-associated protein 29 | protein | 192 | 14% helix, 35% strand | Q9QZ88 |
| B | Ankyrin repeat domain-containing protein 27 | protein | 61 | 0% helix, 0% strand | Q96NW4 |
Ligands and binding sites
- ZN · Zinc ion · metal · chains B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 91 | 0.35 | 0.74 | 15 | empty |
| 2 | 60 | 0.31 | 0.76 | 18 | empty |
Interfaces
1 interface between chains.
- A–B · 344 Ų buried · 4 hydrogen bonds · protein-protein
Compared structures
- 6TL0 · Solution structure and 1H, 13C and 15N chemical shift assignments for the complex of… · the same entry in another collection · chain A against A, TM-score 1.00
- Q9QZ88 · AlphaFold monomer V2.0 prediction for vacuolar protein sorting- associated protein 29… · a predicted model of the same protein · chain A against A, TM-score 0.93
- Q96NW4 · AlphaFold monomer V2.0 prediction for ankyrin repeat domain- containing protein 27… · a predicted model of the same protein · chain B against A, TM-score 0.34
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9QZ88
- Every structure of UniProt Q96NW4
- Elsewhere: RCSB PDB 6TL0 · PDBe 6TL0 · UniProt Q9QZ88 · UniProt Q96NW4
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