Research workbench
Structure of the five-fold capsomer of the DARC1 capsid
Analyse Structure of the five-fold capsomer of the DARC1 capsid in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6TAR
- Type
- protein
- Length
- 820 residues
- Chains
- 5
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Activity-regulated cytoskeleton associated protein 1
- UniProt
- Q7K1U0
- Pockets
- 14 · best druggability 0.65
Structure
electron microscopy · 1 distinct chain · 58% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, E | Activity-regulated cytoskeleton associated protein 1 | protein | 164 | 58% helix, 1% strand | Q7K1U0 |
Pockets
14 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 582 | 0.65 | 0.76 | 76 | empty |
| 2 | 539 | 0.64 | 0.76 | 86 | empty |
| 3 | 518 | 0.62 | 0.75 | 61 | empty |
| 4 | 307 | 0.60 | 0.78 | 39 | empty |
| 5 | 314 | 0.58 | 0.77 | 37 | empty |
Interfaces
5 interfaces between chains.
- A–B · 1095 Ų buried · 5 hydrogen bonds · protein-protein
- A–E · 1025 Ų buried · 4 hydrogen bonds · protein-protein
- D–E · 1025 Ų buried · 3 hydrogen bonds · protein-protein
- C–D · 1009 Ų buried · 3 hydrogen bonds · protein-protein
- B–C · 939 Ų buried · 3 hydrogen bonds · protein-protein
Compared structures
- 6TAR · Structure of the five-fold capsomer of the dArc1 capsid · the same entry in another collection · chain E against E, TM-score 1.00
- Q7K1U0 · AlphaFold monomer V2.0 prediction for activity-regulated cytoskeleton associated protein… · a predicted model of the same protein · chain A against A, TM-score 0.93
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q7K1U0
- Elsewhere: RCSB PDB 6TAR · PDBe 6TAR · UniProt Q7K1U0
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