UniProt Q7K1U0
Activity-regulated cytoskeleton associated protein 1 (Q7K1U0)
Activity-regulated cytoskeleton associated protein 1 (UniProt Q7K1U0): 12 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 47 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q7K1U0
- Protein
- Activity-regulated cytoskeleton associated protein 1
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 47 · 3 records with a druggable one
Structures
13 records of Q7K1U0 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6S7X | dARC1 capsid domain dimer, orthorhombic form at 1.7 Angstrom | x-ray diffraction | A, B | NA, CL | 2 (best 0.49) |
| 6S7X | DARC1 capsid domain dimer, orthorhombic form at 1.7 ångström | x-ray diffraction | A, B | NA, CL | — |
| 6S7Y | dARC1 capsid domain dimer, hexagonal form at 2.3 Angstrom | x-ray diffraction | A, B | — | 2 (best 0.50) |
| 6S7Y | DARC1 capsid domain dimer, hexagonal form at 2.3 ångström | x-ray diffraction | A, B | — | — |
| 6SID | Crystal structure of the C-lobe of drosophila Arc 1 at atomic resolution | x-ray diffraction | A | — | — |
| 6SID | Crystal structure of the C-lobe of drosophila arc 1 at atomic resolution | x-ray diffraction | A | — | — |
| 6TAP | Structure of the dArc1 capsid | electron microscopy | A, B, C, D, E | ZN | 11 (best 0.66) |
| 6TAP | Structure of the DARC1 capsid | electron microscopy | A, B, C, D, E | ZN | — |
| 6TAR | Structure of the five-fold capsomer of the dArc1 capsid | electron microscopy | A, B, C, D, E | — | 14 (best 0.65) |
| 6TAR | Structure of the five-fold capsomer of the DARC1 capsid | electron microscopy | A, B, C, D, E | — | — |
| 6TAS | Structure of the two-fold capsomer of the dArc1 capsid | electron microscopy | A, B, C, G, D, E, F, H | ZN | 18 (best 0.73) |
| 6TAS | Structure of the two-fold capsomer of the DARC1 capsid | electron microscopy | A, B, C, G, D, E, F, H | ZN | — |
| Q7K1U0 | AlphaFold monomer V2.0 prediction for activity-regulated cytoskeleton associated protein 1 (Q7K1U0) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6SID chain A against the predicted model Q7K1U0: TM-score 0.99, RMSD 0.38 Å
- 6SID chain A against the predicted model Q7K1U0: TM-score 0.99, RMSD 0.38 Å
- 6TAP chain A against the predicted model Q7K1U0: TM-score 0.93, RMSD 1.34 Å
- 6TAR chain A against the predicted model Q7K1U0: TM-score 0.93, RMSD 1.34 Å
- 6TAP chain A against the predicted model Q7K1U0: TM-score 0.93, RMSD 1.34 Å
- 6TAR chain A against the predicted model Q7K1U0: TM-score 0.93, RMSD 1.34 Å
- 6TAR chain C against the predicted model Q7K1U0: TM-score 0.93, RMSD 1.34 Å
- 6TAR chain C against the predicted model Q7K1U0: TM-score 0.93, RMSD 1.34 Å
- 6TAR chain E against the predicted model Q7K1U0: TM-score 0.93, RMSD 1.34 Å
- 6TAR chain E against the predicted model Q7K1U0: TM-score 0.93, RMSD 1.34 Å
Elsewhere
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