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Crystal structure of P. aeruginosa pqsl: R41Y, I43R, G45R, C105G mutant

Analyse Crystal structure of P. aeruginosa pqsl: R41Y, I43R, G45R, C105G mutant in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6SW1
Type: protein
Length: 367 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Probable FAD-dependent monooxygenase
UniProt: Q9HWJ1
Ligands: FAD, PO4
Pockets: 2 · best druggability 0.80

Structure

x-ray diffraction · 1 distinct chain · 38% helix, 26% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Probable FAD-dependent monooxygenase	protein	367	38% helix, 26% strand	Q9HWJ1

Ligands and binding sites

FAD · Flavin-adenine dinucleotide · ligand · chains A
PO4 · Phosphate ion · ion · chains A
PEG · Di(hydroxyethyl)ether · additive · 2 copies · chains A
GOL · Glycerol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	714	0.80	0.84	75	FAD, GOL, PEG
2	51	0.40	0.82	15	empty

Compared structures

6SW1 · Crystal Structure of P. aeruginosa PqsL: R41Y, I43R, G45R, C105G mutant · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9HWJ1
Elsewhere: RCSB PDB 6SW1 · PDBe 6SW1 · UniProt Q9HWJ1

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