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Structure of the human RAB38 in complex with GTP

Analyse Structure of the human RAB38 in complex with GTP in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6S5H
Type: protein
Length: 175 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: RAS-related protein rab-38
UniProt: P57729
Ligands: GTP, MG, BR
Pockets: 1 · best druggability 0.56

Structure

x-ray diffraction · 1 distinct chain · 34% helix, 31% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	RAS-related protein rab-38	protein	175	34% helix, 31% strand	P57729

Ligands and binding sites

GTP · Guanosine-5'-triphosphate · ligand · chains A
MG · Magnesium ion · metal · chains A
BR · Bromide ion · ion · 3 copies · chains A
EDO · 1,2-ethanediol · additive · 9 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	181	0.56	0.81	34	GTP, MG

Compared structures

6S5H · Structure of the human RAB38 in complex with GTP · the same entry in another collection · chain A against A, TM-score 1.00
P57729 · AlphaFold monomer V2.0 prediction for RAS-related protein rab-38 (P57729) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P57729
Elsewhere: RCSB PDB 6S5H · PDBe 6S5H · UniProt P57729

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