Research workbench
Sivrcm intasome in complex with bictegravir
Analyse Sivrcm intasome in complex with bictegravir in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6RWM
- Type
- protein + DNA
- Length
- 2,162 residues
- Chains
- 16
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- E1ANT8
- Ligands
- KLQ, ZN, MG, CL
Structure
electron microscopy · 8 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, I | — | protein | 270 | — | E1ANT8 |
| B, J | — | protein | 252 | — | E1ANT8 |
| C, K | — | protein | 193 | — | E1ANT8 |
| D, L | — | protein | 207 | — | E1ANT8 |
| F, N | — | protein | 69 | — | E1ANT8 |
| M, E | — | protein | 47 | — | E1ANT8 |
| T, W | — | dna | 20 | — | — |
| S, Q | — | dna | 23 | — | — |
Ligands and binding sites
- KLQ · Bictegravir · ligand · 2 copies · chains A, T, S, I, W, Q
- ZN · Zinc ion · metal · 8 copies · chains A, B, C, M, I, J, K, E
- MG · Magnesium ion · metal · 4 copies · chains A, I
- CL · Chloride ion · ion · 2 copies · chains A, I
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6RWM · SIVrcm intasome in complex with bictegravir · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt E1ANT8
- Elsewhere: RCSB PDB 6RWM · PDBe 6RWM · UniProt E1ANT8
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