Research workbench
X-ray crystal structure of carbonic anhydrase XII complexed with a theranostic monoclonal antibody fragment
Analyse X-ray crystal structure of carbonic anhydrase XII complexed with a theranostic… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6RPS
- Type
- protein
- Length
- 1,386 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- O43570
- Ligands
- CD, ZN, SO4, CL
Structure
x-ray diffraction · 3 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | — | protein | 262 | — | O43570 |
| M, L | — | protein | 214 | — | — |
| N, H | — | protein | 217 | — | — |
Ligands and binding sites
- CD · Cadmium ion · metal · 4 copies · chains A, B
- ZN · Zinc ion · metal · 2 copies · chains A, B
- SO4 · Sulfate ion · ion · 2 copies · chains A, H, B, N
- CL · Chloride ion · ion · chains A
- ACT · Acetate ion · additive · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6RPS · X-ray crystal structure of carbonic anhydrase XII complexed with a theranostic monoclonal… · the same entry in another collection · chain H against H, TM-score 1.00
- O43570 · AlphaFold monomer V2.0 prediction for carbonic anhydrase 12 (O43570) · a predicted model of the same protein · chain B against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O43570
- Elsewhere: RCSB PDB 6RPS · PDBe 6RPS · UniProt O43570
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