Research workbench
Transposase inhibitor
Analyse Transposase inhibitor in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1B7E
- Type
- protein
- Length
- 372 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Protein (transposase inhibitor protein from TN5)
- Ligands
- TPT
- Pockets
- 7 · best druggability 0.71
Structure
x-ray diffraction · 1 distinct chain · 45% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Protein (transposase inhibitor protein from TN5) | protein | 372 | 45% helix, 21% strand | — |
Ligands and binding sites
- TPT · 2,2':6',2''-TERPYRIDINE PLATINUM(II) Chloride · ligand · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 555 | 0.71 | 0.80 | 37 | empty |
| 2 | 59 | 0.70 | 0.96 | 20 | empty |
| 3 | 152 | 0.48 | 0.77 | 23 | empty |
| 4 | 136 | 0.44 | 0.76 | 20 | empty |
| 5 | 81 | 0.36 | 0.77 | 20 | empty |
Compared structures
- 1B7E · Transposase inhibitor · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 1B7E · PDBe 1B7E
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.