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Ligand · TPT

TPT · 2,2':6',2''-TERPYRIDINE PLATINUM(II) Chloride

TPT, 2,2':6',2''-TERPYRIDINE PLATINUM(II) Chloride (C15 H11 Cl N3 Pt +1, 463.8 g/mol), in the MolNFT structures on GenesisL1: bound in 12 records (6 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds…

Component
TPT
Formula
C15 H11 Cl N3 Pt +1
Class
ligand
Structures
12
PDB entries
6

Binding sites

TPT in 12 structures; the first of them:

  • 1B7E · Transposase inhibitor · TPT A480 · binds GLU394, PRO399, CYS402, GLN403, GLY406, TRP424
  • 1HCX · Choline binding domain of the major autolysin (C-LytA) from Streptococcus pneumoniae · TPT A1319 · binds TRP241, TRP248, TYR264, TYR269, MET278, ASP298
  • 1QNQ · The 3-D structure of a Trichoderma reesei b-mannanase from glycoside hydrolase family 5 · TPT A401 · binds TYR243, SER246, TRP306, ASP321, TYR323
  • 2ZZB · Crystal structure of human thioredoxin reductase I and terpyridine platinum(II) · TPT B501 · binds ASN107, SER111, TRP114
  • 3RO0 · Crystal structure of Bacillus amyloliquefaciens pyroglutamyl peptidase I and terpyridine… · TPT A480 · binds PHE10, ASP11, PHE13, ASN19, THR45, GLN71, ILE92, ALA139 and 4 more
  • 3RO1 · Crystal structure of the complex of the archaeal sulfolobus PTP-fold phosphatase with… · TPT A165 · binds TRP39, GLU43
  • 1B7E · Transposase inhibitor · TPT A480 · binds GLU394, PRO399, CYS402, GLN403, GLY406, TRP424
  • 1HCX · Choline binding domain of the major autolysin (C-lyta) from streptococcus pneumoniae · TPT A1319 · binds TRP241, TRP248, TYR264, TYR269, MET278, ASP298
  • 1QNQ · The 3-D structure of a trichoderma reesei B-mannanase from glycoside hydrolase family 5 · TPT A401 · binds TYR243, SER246, TRP306, ASP321, TYR323
  • 2ZZB · Crystal structure of human thioredoxin reductase I and terpyridine PLATINUM(II) · TPT B501 · binds ASN107, SER111, TRP114
  • 3RO0 · Crystal structure of bacillus amyloliquefaciens pyroglutamyl peptidase I and terpyridine… · TPT A480 · binds PHE10, ASP11, PHE13, ASN19, THR45, GLN71, ILE92, ALA139 and 4 more
  • 3RO1 · Crystal structure of the complex of the archaeal sulfolobus ptp-fold phosphatase with… · TPT A165 · binds TRP39, GLU43

Residues it binds most

PHE 8, HIS 12, TRP 14, ASN 12, CYS 12, GLY 12, GLN 10, GLU 8, TYR 6, ALA 8 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion
  • CHT · Choline ion
  • DDQ · Decylamine-N,N-dimethyl-N-oxide
  • FAD · Flavin-adenine dinucleotide
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose

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