Human cyclophilin D in complex with norbornane fragment derivative

Structure

x-ray diffraction · 1 distinct chain · 15% helix, 31% strand (DSSP).

Ligands and binding sites

• JWB · 2-[(1~{R},2~{R},6~{S},7~{S})-3,5-bis(oxidanylidene)-4-azatricyclo[5.2.1.0^{2,6}]decan-4-yl]ethanoic acid · ligand · chains A
• JVQ · 14-ethyl-4,6-dioxa-10,14-diazatricyclo[7.6.0.0^{3, 7}]pentadeca-1(9),2,7-trien-13-one · ligand · chains A
• SO4 · Sulfate ion · ion · 2 copies · chains A
• PEG · Di(hydroxyethyl)ether · additive · chains A
• PG4 · Tetraethylene glycol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

• 6RA1 · Human Cyclophilin D in complex with norbornane fragment derivative · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P30405
• Elsewhere: RCSB PDB 6RA1 · PDBe 6RA1 · UniProt P30405