Research workbench

Structure of saccharomyces cerevisiae apo PAN2 pseudoubiquitin hydrolase-RNA exonuclease (uch-exo) module

Analyse Structure of saccharomyces cerevisiae apo PAN2 pseudoubiquitin hydrolase-RNA… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6R9I
Type: protein
Length: 605 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: PAN2-PAN3 deadenylation complex catalytic subunit PAN2
EC: 3.1.13.4
UniProt: P53010
Pockets: 6 · best druggability 0.70

Structure

x-ray diffraction · 1 distinct chain · 32% helix, 22% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	PAN2-PAN3 deadenylation complex catalytic subunit PAN2 (EC 3.1.13.4)	protein	605	32% helix, 22% strand	P53010

Pockets

6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	687	0.70	0.78	66	empty
2	156	0.58	0.82	27	empty
3	163	0.50	0.78	28	empty
4	262	0.49	0.74	34	empty
5	153	0.47	0.77	20	empty

Compared structures

6R9I · Structure of Saccharomyces cerevisiae apo Pan2 pseudoubiquitin hydrolase-RNA exonuclease… · the same entry in another collection · chain A against A, TM-score 1.00
P53010 · AlphaFold monomer V2.0 prediction for PAN2-PAN3 deadenylation complex catalytic subunit… · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P53010
Elsewhere: RCSB PDB 6R9I · PDBe 6R9I · UniProt P53010

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.