UniProt P53010
PAN2-PAN3 deadenylation complex catalytic subunit PAN2 (P53010)
PAN2-PAN3 deadenylation complex catalytic subunit PAN2 (UniProt P53010), EC 3.1.13.4: 20 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 165 pockets. Binding sites, druggability and experiment against…
- UniProt
- P53010
- Protein
- PAN2-PAN3 deadenylation complex catalytic subunit PAN2
- EC
- 3.1.13.4
- Experimental structures
- 20
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 165 · 19 records with a druggable one
Structures
21 records of P53010 in the MolNFT archive: 20 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4Q8G | Structure of the Saccharomyces cerevisiae PAN2 pseudoubiquitin-hydrolase | x-ray diffraction | A, B | ZN | 4 (best 0.43) |
| 4Q8G | Structure of the saccharomyces cerevisiae PAN2 pseudoubiquitin- hydrolase | x-ray diffraction | A, B | ZN | 4 (best 0.43) |
| 4Q8H | Structure of the Saccharomyces cerevisiae PAN2 pseudoubiquitin-hydrolase-RNase module | x-ray diffraction | A | MG | 5 (best 0.77) |
| 4Q8H | Structure of the saccharomyces cerevisiae PAN2 pseudoubiquitin- hydrolase-RNase module | x-ray diffraction | A | MG | 5 (best 0.77) |
| 4XR7 | Structure of the Saccharomyces cerevisiae PAN2-PAN3 core complex | x-ray diffraction | G, D, J, A | — | 15 (best 0.84) |
| 4XR7 | Structure of the saccharomyces cerevisiae PAN2-PAN3 core complex | x-ray diffraction | G, D, J, A | — | 15 (best 0.84) |
| 6R5K | Cryo-EM structure of a poly(A) RNP bound to the Pan2-Pan3 deadenylase | electron microscopy | A | MG | 13 (best 0.84) |
| 6R5K | Cryo-EM structure of a POLY(A) rnp bound to the PAN2-PAN3 deadenylase | electron microscopy | A | MG | 13 (best 0.84) |
| 6R9I | Structure of Saccharomyces cerevisiae apo Pan2 pseudoubiquitin hydrolase-RNA exonuclease (UCH-Exo)… | x-ray diffraction | A | — | 6 (best 0.70) |
| 6R9I | Structure of saccharomyces cerevisiae apo PAN2 pseudoubiquitin hydrolase-RNA exonuclease (uch-exo)… | x-ray diffraction | A | — | 6 (best 0.70) |
| 6R9J | Structure of Saccharomyces cerevisiae apo Pan2 pseudoubiquitin hydrolase-RNA exonuclease (UCH-Exo)… | x-ray diffraction | A | — | 6 (best 0.74) |
| 6R9J | Structure of saccharomyces cerevisiae apo PAN2 pseudoubiquitin hydrolase-RNA exonuclease (uch-exo)… | x-ray diffraction | A | — | 6 (best 0.74) |
| 6R9M | Structure of Saccharomyces cerevisiae apo Pan2 pseudoubiquitin hydrolase-RNA exonuclease (UCH-Exo)… | x-ray diffraction | A | — | 8 (best 0.75) |
| 6R9M | Structure of saccharomyces cerevisiae apo PAN2 pseudoubiquitin hydrolase-RNA exonuclease (uch-exo)… | x-ray diffraction | A | — | 8 (best 0.75) |
| 6R9O | Structure of Saccharomyces cerevisiae apo Pan2 pseudoubiquitin hydrolase-RNA exonuclease (UCH-Exo)… | x-ray diffraction | A | — | 6 (best 0.75) |
| 6R9O | Structure of saccharomyces cerevisiae apo PAN2 pseudoubiquitin hydrolase-RNA exonuclease (uch-exo)… | x-ray diffraction | A | — | 6 (best 0.75) |
| 6R9P | Structure of Saccharomyces cerevisiae apo Pan2 pseudoubiquitin hydrolase-RNA exonuclease (UCH-Exo)… | x-ray diffraction | A | — | 7 (best 0.73) |
| 6R9P | Structure of saccharomyces cerevisiae apo PAN2 pseudoubiquitin hydrolase-RNA exonuclease (uch-exo)… | x-ray diffraction | A | — | 7 (best 0.73) |
| 6R9Q | Structure of Saccharomyces cerevisiae apo Pan2 pseudoubiquitin hydrolase-RNA exonuclease (UCH-Exo)… | x-ray diffraction | A | — | 6 (best 0.75) |
| 6R9Q | Structure of saccharomyces cerevisiae apo PAN2 pseudoubiquitin hydrolase-RNA exonuclease (uch-exo)… | x-ray diffraction | A | — | 6 (best 0.75) |
| P53010 | AlphaFold monomer V2.0 prediction for PAN2-PAN3 deadenylation complex catalytic subunit PAN2… | predicted | A | — | 13 (best 0.83) |
Ligands
Experiment against prediction
- 6R9O chain A against the predicted model P53010: TM-score 0.98, RMSD 1.18 Å
- 6R9O chain A against the predicted model P53010: TM-score 0.98, RMSD 1.18 Å
- 6R9J chain A against the predicted model P53010: TM-score 0.98, RMSD 1.29 Å
- 6R9J chain A against the predicted model P53010: TM-score 0.98, RMSD 1.29 Å
- 6R9M chain A against the predicted model P53010: TM-score 0.98, RMSD 1.31 Å
- 6R9M chain A against the predicted model P53010: TM-score 0.98, RMSD 1.31 Å
- 4Q8G chain A against the predicted model P53010: TM-score 0.98, RMSD 1.05 Å
- 4Q8G chain A against the predicted model P53010: TM-score 0.98, RMSD 1.05 Å
- 6R9P chain A against the predicted model P53010: TM-score 0.98, RMSD 1.37 Å
- 6R9P chain A against the predicted model P53010: TM-score 0.98, RMSD 1.37 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.