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MolNFT v1 · #162328 · protein + RNA

Cryo-EM structure of a POLY(A) rnp bound to the PAN2-PAN3 deadenylase

6R5K: “Cryo-EM structure of a POLY(A) rnp bound to the PAN2-PAN3 deadenylase”. Electron microscopy, 1 ligand (MG). MolNFT v1 #162328 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
6R5K
Type
protein + RNA
Length
2,932 residues
Chains
7
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
P53010, P04147, P36102
Ligands
MG

Structure

electron microscopy · 7 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein1040—P53010
D—protein390—P04147
E—rna67——
F—protein165—P04147
H—protein394—P04147
N—protein429—P36102
O—protein447—P36102

Ligands and binding sites

  • MG · Magnesium ion · metal · 2 copies · chains A, E

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 6R5K · Cryo-EM structure of a poly(A) RNP bound to the Pan2-Pan3 deadenylase · the same entry in another collection · chain O against O, TM-score 1.00
  • P36102 · AlphaFold monomer V2.0 prediction for PAN2-PAN3 deadenylation complex subunit PAN3… · a predicted model of the same protein · chain O against A, TM-score 0.92
  • P53010 · AlphaFold monomer V2.0 prediction for PAN2-PAN3 deadenylation complex catalytic subunit… · a predicted model of the same protein · chain A against A, TM-score 0.72
  • P04147 · AlphaFold monomer V2.0 prediction for polyadenylate-binding protein, cytoplasmic and… · a predicted model of the same protein · chain F against A, TM-score 0.72

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