Research workbench
Bovine serum albumin in complex with ketoprofen
Analyse Bovine serum albumin in complex with ketoprofen in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6QS9
- Type
- protein
- Length
- 1,156 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Serum albumin
- UniProt
- P02769
- Ligands
- JGE, CA
- Pockets
- 17 · best druggability 0.82
Structure
x-ray diffraction · 2 distinct chains · 72% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Serum albumin | protein | 580 | 72% helix, 0% strand | P02769 |
| B | Serum albumin | protein | 576 | 72% helix, 0% strand | P02769 |
Ligands and binding sites
- JGE · (R)-Ketoprofen · ligand · 2 copies · chains A, B
- CA · Calcium ion · metal · 4 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
17 pockets found on a 1 Å grid, 12 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 750 | 0.82 | 0.85 | 76 | JGE |
| 2 | 528 | 0.79 | 0.86 | 70 | empty |
| 3 | 828 | 0.78 | 0.81 | 64 | empty |
| 4 | 424 | 0.77 | 0.86 | 41 | JGE |
| 5 | 935 | 0.77 | 0.79 | 78 | empty |
Interfaces
1 interface between chains.
- A–B · 361 Ų buried · 8 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 34 disulfide (disulfide).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P02769
- Elsewhere: RCSB PDB 6QS9 · PDBe 6QS9 · UniProt P02769
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.