Research workbench

Re-refinement of 5OLI human IBA57-I3C

Analyse Re-refinement of 5OLI human IBA57-I3C in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6QE4
Type: protein
Length: 308 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Putative transferase CAF17, mitochondrial
EC: 2.1.-.-
UniProt: Q5T440
Ligands: I3C
Pockets: 3 · best druggability 0.42

Structure

x-ray diffraction · 1 distinct chain · 17% helix, 34% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Putative transferase CAF17, mitochondrial (EC 2.1.-.-)	protein	308	17% helix, 34% strand	Q5T440

Ligands and binding sites

I3C · 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid · ligand · 4 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	111	0.42	0.77	23	empty
2	143	0.39	0.73	27	empty
3	68	0.38	0.79	23	empty

Compared structures

6QE4 · Re-refinement of 5OLI human IBA57-I3C · the same entry in another collection · chain A against A, TM-score 1.00
Q5T440 · AlphaFold monomer V2.0 prediction for putative transferase CAF17, mitochondrial (Q5T440) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q5T440
Elsewhere: RCSB PDB 6QE4 · PDBe 6QE4 · UniProt Q5T440

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