Research workbench
Mscs nanodisc
Analyse Mscs nanodisc in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6PWP
- Type
- protein
- Length
- 1,960 residues
- Chains
- 7
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Small-conductance mechanosensitive channel
- UniProt
- P0C0S1
- Pockets
- 20 · best druggability 0.85
Structure
electron microscopy · 1 distinct chain · 53% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, E, F, G | Small-conductance mechanosensitive channel | protein | 280 | 53% helix, 20% strand | P0C0S1 |
Pockets
20 pockets found on a 1 Å grid, 20 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 410 | 0.85 | 0.92 | 35 | empty |
| 2 | 592 | 0.77 | 0.83 | 82 | empty |
| 3 | 1128 | 0.71 | 0.75 | 50 | empty |
| 4 | 466 | 0.69 | 0.80 | 56 | empty |
| 5 | 305 | 0.69 | 0.83 | 45 | empty |
Interfaces
14 interfaces between chains.
- C–D · 2774 Ų buried · 31 hydrogen bonds · protein-protein
- A–G · 2756 Ų buried · 29 hydrogen bonds · protein-protein
- F–G · 2753 Ų buried · 28 hydrogen bonds · protein-protein
- E–F · 2745 Ų buried · 30 hydrogen bonds · protein-protein
- B–C · 2740 Ų buried · 28 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0C0S1
- Elsewhere: RCSB PDB 6PWP · PDBe 6PWP · UniProt P0C0S1
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.