Research workbench

Poliovirus (type 1 mahoney), heat-catalysed 135S particle

Analyse Poliovirus (type 1 mahoney), heat-catalysed 135S particle in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6PSZ
Type: protein
Length: 646 residues
Chains: 3
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: VP1; VP2; VP3
UniProt: P03300, Q8QYM4
Pockets: 5 · best druggability 0.47

Structure

electron microscopy · 3 distinct chains · 11% helix, 35% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
1	VP1	protein	193	11% helix, 38% strand	P03300
2	VP2	protein	222	11% helix, 36% strand	P03300
3	VP3	protein	231	10% helix, 30% strand	Q8QYM4

Pockets

5 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	243	0.47	0.73	30	empty
2	57	0.45	0.84	18	empty
3	114	0.42	0.77	26	empty
4	71	0.37	0.77	18	empty
5	89	0.33	0.74	18	empty

Interfaces

3 interfaces between chains.

1–3 · 2300 Å² buried · 36 hydrogen bonds · protein-protein
2–3 · 1611 Å² buried · 21 hydrogen bonds · protein-protein
1–2 · 966 Å² buried · 9 hydrogen bonds · protein-protein

Compared structures

6PSZ · Poliovirus (Type 1 Mahoney), heat-catalysed 135S particle · the same entry in another collection · chain 1 against 1, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P03300
Every structure of UniProt Q8QYM4
Elsewhere: RCSB PDB 6PSZ · PDBe 6PSZ · UniProt P03300 · UniProt Q8QYM4

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