Structure of human endotheial nitric oxide synthase heme domain in complex with 7-(5-(AMINOMETHYL)PYRIDIN-3-yl)-4-methylquinolin-2-amine

Structure

x-ray diffraction · 3 distinct chains.

Ligands and binding sites

• OUA · 7-[5-(aminomethyl)pyridin-3-yl]-4-methylquinolin-2-amine · ligand · 6 copies · chains A, B, C, D
• HEM · Protoporphyrin IX containing Fe · ligand · 4 copies · chains A, B, C, D
• H4B · 5,6,7,8-tetrahydrobiopterin · ligand · 2 copies · chains A, B, C, D
• GD · Gadolinium atom · metal · 4 copies · chains B, C, D
• ZN · Zinc ion · metal · 2 copies · chains A, B, C, D
• CL · Chloride ion · ion · 4 copies · chains A, B, C, D
• BTB · 2-[bis-(2-hydroxy-ethyl)-amino]-2-hydroxymethyl-propane-1,3-diol · additive · 9 copies · chains A, C, B, D
• GOL · Glycerol · additive · 2 copies · chains A, C

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

• 6POW · Structure of human endotheial nitric oxide synthase heme domain in complex with… · the same entry in another collection · chain A against A, TM-score 1.00

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• Elsewhere: RCSB PDB 6POW · PDBe 6POW · UniProt P29474