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Mismatch repair in methylated DNA. structure of the mismatch-specific thymine glycosylase domain of methyl-cpg-binding protein MBD4

Analyse Mismatch repair in methylated DNA. structure of the mismatch-specific thymine… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1NGN
Type: protein
Length: 144 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Methyl-cpg binding protein MBD4
UniProt: Q9Z2D7
Pockets: 1 · best druggability 0.35

Structure

x-ray diffraction · 1 distinct chain · 66% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Methyl-cpg binding protein MBD4	protein	144	66% helix, 0% strand	Q9Z2D7

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	79	0.35	0.76	15	empty

Compared structures

1NGN · Mismatch repair in methylated DNA. Structure of the mismatch-specific thymine glycosylase… · the same entry in another collection · chain A against A, TM-score 1.00
Q9Z2D7 · AlphaFold monomer V2.0 prediction for methyl-cpg-binding domain protein 4 (Q9Z2D7) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9Z2D7
Elsewhere: RCSB PDB 1NGN · PDBe 1NGN · UniProt Q9Z2D7

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