UniProt Q9Z2D7
Methyl-cpg-binding domain protein 4 (Q9Z2D7)
Methyl-cpg-binding domain protein 4 (UniProt Q9Z2D7): 16 experimental structures and 1 predicted model on GenesisL1, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9Z2D7
- Protein
- Methyl-cpg-binding domain protein 4
- Experimental structures
- 16
- Predicted models
- 1
- Pockets
- 3 · 0 records with a druggable one
Structures
17 records of Q9Z2D7 in the MolNFT archive: 16 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1NGN | Mismatch repair in methylated DNA. Structure of the mismatch-specific thymine glycosylase domain of… | x-ray diffraction | A | — | — |
| 1NGN | Mismatch repair in methylated DNA. structure of the mismatch-specific thymine glycosylase domain of… | x-ray diffraction | A | — | — |
| 3VXV | Crystal structure of methyl CpG Binding Domain of MBD4 in complex with the 5mCG/TG sequence | x-ray diffraction | A | — | — |
| 3VXV | Crystal structure of methyl cpg binding domain of MBD4 in complex with the 5MCG/TG sequence | x-ray diffraction | A | — | — |
| 3VXX | Crystal structure of methyl CpG binding domain of MBD4 in complex with the 5mCG/5mCG sequence | x-ray diffraction | A | — | — |
| 3VXX | Crystal structure of methyl cpg binding domain of MBD4 in complex with the 5MCG/5MCG sequence | x-ray diffraction | A | — | — |
| 3VYB | Crystal structure of methyl CpG binding domain of MBD4 in complex with the 5mCG/hmCG sequence | x-ray diffraction | A | — | — |
| 3VYB | Crystal structure of methyl cpg binding domain of MBD4 in complex with the 5MCG/HMCG sequence | x-ray diffraction | A | — | — |
| 3VYQ | Crystal structure of the methyl CpG Binding Domain of MBD4 in complex with the 5mCG/TG sequence in… | x-ray diffraction | A, D | — | — |
| 3VYQ | Crystal structure of the methyl cpg binding domain of MBD4 in complex with the 5MCG/TG sequence in… | x-ray diffraction | A, D | — | — |
| 4EVV | mouse MBD4 glycosylase domain in complex with a G:T mismatch | x-ray diffraction | A | — | — |
| 4EVV | Mouse MBD4 glycosylase domain in complex with a G:T mismatch | x-ray diffraction | A | — | — |
| 4EW0 | mouse MBD4 glycosylase domain in complex with a G:5hmU (5-hydroxymethyluracil) mismatch | x-ray diffraction | A | — | — |
| 4EW0 | Mouse MBD4 glycosylase domain in complex with a G:5HMU (5- hydroxymethyluracil) mismatch | x-ray diffraction | A | — | — |
| 4EW4 | mouse MBD4 glycosylase domain in complex with DNA containing a ribose sugar | x-ray diffraction | A | — | — |
| 4EW4 | Mouse MBD4 glycosylase domain in complex with DNA containing a ribose sugar | x-ray diffraction | A | — | — |
| Q9Z2D7 | AlphaFold monomer V2.0 prediction for methyl-cpg-binding domain protein 4 (Q9Z2D7) | predicted | A | — | 3 (best 0.35) |
Experiment against prediction
- 4EVV chain A against the predicted model Q9Z2D7: TM-score 0.99, RMSD 0.40 Å
- 4EVV chain A against the predicted model Q9Z2D7: TM-score 0.99, RMSD 0.40 Å
- 4EW0 chain A against the predicted model Q9Z2D7: TM-score 0.99, RMSD 0.44 Å
- 4EW0 chain A against the predicted model Q9Z2D7: TM-score 0.99, RMSD 0.44 Å
- 4EW4 chain A against the predicted model Q9Z2D7: TM-score 0.99, RMSD 0.45 Å
- 4EW4 chain A against the predicted model Q9Z2D7: TM-score 0.99, RMSD 0.45 Å
- 1NGN chain A against the predicted model Q9Z2D7: TM-score 0.98, RMSD 0.57 Å
- 1NGN chain A against the predicted model Q9Z2D7: TM-score 0.98, RMSD 0.57 Å
- 3VYQ chain A against the predicted model Q9Z2D7: TM-score 0.95, RMSD 0.67 Å
- 3VYQ chain A against the predicted model Q9Z2D7: TM-score 0.95, RMSD 0.67 Å
Elsewhere
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