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Structure of autoinhibited P47PHOX

Analyse Structure of autoinhibited P47PHOX in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1NG2
Type: protein
Length: 176 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Neutrophil cytosolic factor 1
UniProt: P14598
Pockets: 3 · best druggability 0.45

Structure

x-ray diffraction · 1 distinct chain · 13% helix, 26% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Neutrophil cytosolic factor 1	protein	176	13% helix, 26% strand	P14598

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	108	0.45	0.79	23	empty
2	147	0.45	0.75	18	empty
3	74	0.28	0.72	21	empty

Compared structures

1NG2 · Structure of autoinhibited p47phox · the same entry in another collection · chain A against A, TM-score 1.00
P14598 · AlphaFold monomer V2.0 prediction for neutrophil cytosol factor 1 (P14598) · a predicted model of the same protein · chain A against A, TM-score 0.76

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P14598
Elsewhere: RCSB PDB 1NG2 · PDBe 1NG2 · UniProt P14598

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