Research workbench
Crystal structure of diras 2/3 chimera in complex with GDP
Analyse Crystal structure of diras 2/3 chimera in complex with GDP in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6NAZ
- Type
- protein
- Length
- 157 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- GTP-binding protein di-RAS2,GTP-binding protein di-RAS3, GTP-binding protein di-RAS2
- UniProt
- Q96HU8, O95661
- Ligands
- GDP
- Pockets
- 1 · best druggability 0.50
Structure
x-ray diffraction · 1 distinct chain · 37% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | GTP-binding protein di-RAS2,GTP-binding protein di-RAS3, GTP-binding protein di-RAS2 | protein | 157 | 37% helix, 20% strand | Q96HU8, O95661 |
Ligands and binding sites
- GDP · Guanosine-5'-diphosphate · ligand · chains A
- GOL · Glycerol · additive · 3 copies · chains A
- EDO · 1,2-ethanediol · additive · 3 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 173 | 0.50 | 0.78 | 29 | GDP |
Compared structures
- 6NAZ · Crystal structure of DIRAS 2/3 chimera in complex with GDP · the same entry in another collection · chain A against A, TM-score 1.00
- Q96HU8 · AlphaFold monomer V2.0 prediction for GTP-binding protein di-RAS2 (Q96HU8) · a predicted model of the same protein · chain A against A, TM-score 0.90
- O95661 · AlphaFold monomer V2.0 prediction for GTP-binding protein di-RAS3 (O95661) · a predicted model of the same protein · chain A against A, TM-score 0.90
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q96HU8
- Every structure of UniProt O95661
- Elsewhere: RCSB PDB 6NAZ · PDBe 6NAZ · UniProt Q96HU8 · UniProt O95661
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