Research workbench
Crystal structure of abin-1 uban in complex with one M1-linked di- ubiquitin
Analyse Crystal structure of abin-1 uban in complex with one M1-linked di- ubiquitin in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6N5M
- Type
- protein
- Length
- 276 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Polyubiquitin-C; TNFAIP3-interacting protein 1
- UniProt
- P0CG50, Q9WUU8
- Pockets
- 1 · best druggability 0.28
Structure
x-ray diffraction · 3 distinct chains · 52% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Polyubiquitin-C | protein | 152 | 19% helix, 37% strand | P0CG50 |
| B | TNFAIP3-interacting protein 1 | protein | 62 | 92% helix, 0% strand | Q9WUU8 |
| D | TNFAIP3-interacting protein 1 | protein | 62 | 92% helix, 0% strand | Q9WUU8 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 66 | 0.28 | 0.73 | 16 | empty |
Interfaces
3 interfaces between chains.
- B–D · 1778 Ų buried · 7 hydrogen bonds · protein-protein
- A–D · 665 Ų buried · 6 hydrogen bonds · protein-protein
- A–B · 595 Ų buried · 12 hydrogen bonds · protein-protein
Compared structures
- 6N5M · Crystal structure of ABIN-1 UBAN in complex with one M1-linked di-ubiquitin · the same entry in another collection · chain A against A, TM-score 1.00
- Q9WUU8 · AlphaFold monomer V2.0 prediction for TNFAIP3-interacting protein 1 (Q9WUU8) · a predicted model of the same protein · chain D against A, TM-score 0.93
- P0CG50 · AlphaFold monomer V2.0 prediction for polyubiquitin-C (P0CG50) · a predicted model of the same protein · chain A against A, TM-score 0.82
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0CG50
- Every structure of UniProt Q9WUU8
- Elsewhere: RCSB PDB 6N5M · PDBe 6N5M · UniProt P0CG50 · UniProt Q9WUU8
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