Research workbench
Structure of NEMO(51-112) with N- and C-terminal coiled-coil adaptors.
Analyse Structure of NEMO(51-112) with N- and C-terminal coiled-coil adaptors. in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6MI3
- Type
- protein
- Length
- 246 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Nf-kb essential MODULATOR,NF-kappa-B essential modulator, nf-kb essential modulator
- UniProt
- Q9Y6K9
- Pockets
- 1 · best druggability 0.31
Structure
x-ray diffraction · 2 distinct chains · 95% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Nf-kb essential MODULATOR,NF-kappa-B essential modulator, nf-kb essential modulator | protein | 122 | 96% helix, 0% strand | Q9Y6K9 |
| B | Nf-kb essential MODULATOR,NF-kappa-B essential modulator, nf-kb essential modulator | protein | 124 | 94% helix, 0% strand | Q9Y6K9 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 68 | 0.31 | 0.74 | 13 | empty |
Interfaces
1 interface between chains.
- A–B · 3120 Ų buried · 9 hydrogen bonds · protein-protein
Compared structures
- 6MI3 · Structure of NEMO(51-112) with N- and C-terminal coiled-coil adaptors. · the same entry in another collection · chain A against A, TM-score 1.00
- Q9Y6K9 · AlphaFold monomer V2.0 prediction for nf-kappa-B essential modulator (Q9Y6K9) · a predicted model of the same protein · chain B against A, TM-score 0.88
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9Y6K9
- Elsewhere: RCSB PDB 6MI3 · PDBe 6MI3 · UniProt Q9Y6K9
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