UniProt Q9Y6K9
NF-kappa-B essential modulator (Q9Y6K9)
NF-kappa-B essential modulator (UniProt Q9Y6K9): 21 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9Y6K9
- Protein
- NF-kappa-B essential modulator
- Experimental structures
- 21
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 5 · 1 record with a druggable one
Structures
22 records of Q9Y6K9 in the MolNFT archive: 21 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2JVX | Solution Structure of human NEMO zinc finger | solution nmr | A | — | — |
| 2JVX | Solution structure of human nemo zinc finger | solution nmr | A | — | — |
| 2JVY | Solution Structure of the EDA-ID-related C417F mutant of human NEMO zinc finger | solution nmr | A | — | — |
| 2JVY | Solution structure of the eda-id-related C417F mutant of human nemo zinc finger | solution nmr | A | — | — |
| 3BRT | NEMO/IKK association domain structure | x-ray diffraction | B, D | — | — |
| 3BRT | NEMO/IKK association domain structure | x-ray diffraction | B, D | — | — |
| 3BRV | NEMO/IKKb association domain structure | x-ray diffraction | B, D | — | — |
| 3BRV | NEMO/IKKB association domain structure | x-ray diffraction | B, D | — | — |
| 3CL3 | Crystal Structure of a vFLIP-IKKgamma complex: Insights into viral activation of the IKK signalosome | x-ray diffraction | D, E | — | — |
| 3CL3 | Crystal structure of a vflip-ikkgamma complex: insights into viral activation of the ikk signalosome | x-ray diffraction | D, E | — | — |
| 3FX0 | Crystal structure of Human NEMO CC2_LZ domain | x-ray diffraction | A, B | — | — |
| 3FX0 | Crystal structure of human nemo CC2_LZ domain | x-ray diffraction | A, B | — | — |
| 4BWN | Nemo CC2-lz domain | x-ray diffraction | A, B | — | — |
| 4BWN | Nemo CC2-lz domain | x-ray diffraction | A, B | — | — |
| 5AAY | TBK1 recruitment to cytosol-invading Salmonella induces anti- bacterial autophagy | solution nmr | A | ZN | — |
| 5AAY | TBK1 recruitment to cytosol-invading salmonella induces anti- bacterial autophagy | solution nmr | A | — | — |
| 6MI3 | Structure of NEMO(51-112) with N- and C-terminal coiled-coil adaptors. | x-ray diffraction | A, B | — | 1 (best 0.31) |
| 6MI3 | Structure of NEMO(51-112) with N- and C-terminal coiled-coil adaptors. | x-ray diffraction | A, B | — | — |
| 7T2U | SARS-CoV2 3C-Like protease complexed with Nemo peptide | x-ray diffraction | E, F | — | 2 (best 0.76) |
| 7TV4 | Crystal structure of NEMO CoZi in complex with HOIP NZF1 and linear diubiquitin | x-ray diffraction | B, D | — | 2 (best 0.40) |
| 7TV4 | Crystal structure of nemo cozi in complex with hoip NZF1 and linear diubiquitin | x-ray diffraction | B, D | — | — |
| Q9Y6K9 | AlphaFold monomer V2.0 prediction for nf-kappa-B essential modulator (Q9Y6K9) | predicted | A | — | — |
Ligands
- ZN · Zinc ion · in 1 record
Experiment against prediction
- 3CL3 chain D against the predicted model Q9Y6K9: TM-score 0.93, RMSD 0.75 Å
- 3CL3 chain D against the predicted model Q9Y6K9: TM-score 0.93, RMSD 0.75 Å
- 3CL3 chain E against the predicted model Q9Y6K9: TM-score 0.91, RMSD 0.93 Å
- 3CL3 chain E against the predicted model Q9Y6K9: TM-score 0.91, RMSD 0.93 Å
- 3BRV chain B against the predicted model Q9Y6K9: TM-score 0.91, RMSD 0.87 Å
- 3BRV chain B against the predicted model Q9Y6K9: TM-score 0.91, RMSD 0.87 Å
- 3BRT chain B against the predicted model Q9Y6K9: TM-score 0.90, RMSD 0.91 Å
- 3BRT chain B against the predicted model Q9Y6K9: TM-score 0.90, RMSD 0.91 Å
- 6MI3 chain B against the predicted model Q9Y6K9: TM-score 0.88, RMSD 1.78 Å
- 6MI3 chain B against the predicted model Q9Y6K9: TM-score 0.88, RMSD 1.78 Å
Elsewhere
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