Research workbench
Crystal structure of PA4853 (fis) from pseudomonas aeruginosa
Analyse Crystal structure of PA4853 (fis) from pseudomonas aeruginosa in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6M10
- Type
- protein
- Length
- 324 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Putative fis-like DNA-binding protein
- UniProt
- Q9HUW0
- Pockets
- 4 · best druggability 0.42
Structure
x-ray diffraction · 3 distinct chains · 62% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Putative fis-like DNA-binding protein | protein | 83 | 58% helix, 0% strand | Q9HUW0 |
| C, B | Putative fis-like DNA-binding protein | protein | 80 | 65% helix, 0% strand | Q9HUW0 |
| D | Putative fis-like DNA-binding protein | protein | 81 | 63% helix, 0% strand | Q9HUW0 |
Pockets
4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 98 | 0.42 | 0.78 | 17 | empty |
| 2 | 58 | 0.34 | 0.77 | 10 | empty |
| 3 | 54 | 0.33 | 0.78 | 16 | empty |
| 4 | 55 | 0.29 | 0.75 | 9 | empty |
Interfaces
4 interfaces between chains.
- A–B · 1671 Ų buried · 13 hydrogen bonds · protein-protein
- B–D · 321 Ų buried · 5 hydrogen bonds · protein-protein
- A–C · 300 Ų buried · 6 hydrogen bonds · protein-protein
- C–B · 82 Ų buried · 1 hydrogen bond · protein-protein
Compared structures
- 6M10 · Crystal structure of PA4853 (Fis) from Pseudomonas aeruginosa · the same entry in another collection · chain D against D, TM-score 1.00
- Q9HUW0 · AlphaFold monomer V2.0 prediction for putative fis-like DNA-binding protein (Q9HUW0) · a predicted model of the same protein · chain B against A, TM-score 0.88
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9HUW0
- Elsewhere: RCSB PDB 6M10 · PDBe 6M10 · UniProt Q9HUW0
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