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Crystal structure of the cytoplasmic domain of G-protein activated inward rectifier potassium channel 1

Analyse Crystal structure of the cytoplasmic domain of G-protein activated inward… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1N9P
Type: protein
Length: 197 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: G protein-activated inward rectifier potassium channel 1
UniProt: P63250, P35562
Pockets: 1 · best druggability 0.28

Structure

x-ray diffraction · 1 distinct chain · 10% helix, 42% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	G protein-activated inward rectifier potassium channel 1	protein	197	10% helix, 42% strand	P63250, P35562

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	62	0.28	0.74	21	empty

Modifications

Observed in the structure: 8 modified (engineered).

Compared structures

1N9P · Crystal Structure of the Cytoplasmic Domain of G-protein Activated Inward Rectifier… · the same entry in another collection · chain A against A, TM-score 1.00
P63250 · AlphaFold monomer V2.0 prediction for G protein-activated inward rectifier potassium… · a predicted model of the same protein · chain A against A, TM-score 0.86

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P63250
Every structure of UniProt P35562
Elsewhere: RCSB PDB 1N9P · PDBe 1N9P · UniProt P63250 · UniProt P35562

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