UniProt P63250
G protein-activated inward rectifier potassium channel 1 (P63250)
G protein-activated inward rectifier potassium channel 1 (UniProt P63250): 10 experimental structures and 1 predicted model on GenesisL1, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P63250
- Protein
- G protein-activated inward rectifier potassium channel 1
- Experimental structures
- 10
- Predicted models
- 1
- Pockets
- 3 · 1 record with a druggable one
Structures
11 records of P63250 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1N9P | Crystal Structure of the Cytoplasmic Domain of G-protein Activated Inward Rectifier Potassium… | x-ray diffraction | A | — | — |
| 1N9P | Crystal structure of the cytoplasmic domain of G-protein activated inward rectifier potassium… | x-ray diffraction | A | — | — |
| 1U4E | Crystal Structure of Cytoplasmic Domains of GIRK1 channel | x-ray diffraction | A | — | — |
| 1U4E | Crystal structure of cytoplasmic domains of GIRK1 channel | x-ray diffraction | A | — | — |
| 2QKS | Crystal structure of a Kir3.1-prokaryotic Kir channel chimera | x-ray diffraction | A, B | — | — |
| 2QKS | Crystal structure of a KIR3.1-prokaryotic kir channel chimera | x-ray diffraction | A, B | — | — |
| 3K6N | Crystal structure of the S225E mutant Kir3.1 cytoplasmic pore domain | x-ray diffraction | A | — | — |
| 3K6N | Crystal structure of the S225E mutant KIR3.1 cytoplasmic pore domain | x-ray diffraction | A | — | — |
| 5UM4 | Crystal structure of the F255A mutant Kir3.1 cytoplasmic pore domain | x-ray diffraction | A | — | — |
| 5UM4 | Crystal structure of the F255A mutant KIR3.1 cytoplasmic pore domain | x-ray diffraction | A | — | — |
| P63250 | AlphaFold monomer V2.0 prediction for G protein-activated inward rectifier potassium channel 1… | predicted | A | — | 3 (best 0.50) |
Experiment against prediction
- 3K6N chain A against the predicted model P63250: TM-score 0.90, RMSD 0.95 Å
- 3K6N chain A against the predicted model P63250: TM-score 0.90, RMSD 0.95 Å
- 2QKS chain A against the predicted model P63250: TM-score 0.89, RMSD 2.33 Å
- 2QKS chain A against the predicted model P63250: TM-score 0.89, RMSD 2.33 Å
- 1U4E chain A against the predicted model P63250: TM-score 0.88, RMSD 1.12 Å
- 1U4E chain A against the predicted model P63250: TM-score 0.88, RMSD 1.12 Å
- 1N9P chain A against the predicted model P63250: TM-score 0.86, RMSD 1.87 Å
- 1N9P chain A against the predicted model P63250: TM-score 0.86, RMSD 1.87 Å
- 5UM4 chain A against the predicted model P63250: TM-score 0.84, RMSD 1.85 Å
- 5UM4 chain A against the predicted model P63250: TM-score 0.84, RMSD 1.85 Å
Elsewhere
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