MolNFT v1 · #23580 · protein
Crystal structure of cytoplasmic domains of GIRK1 channel
1U4E · G protein-activated inward rectifier potassium channel 1: “Crystal structure of cytoplasmic domains of GIRK1 channel”. X-ray diffraction, 1 pocket (best druggability 0.29). MolNFT v1 #23580 on GenesisL1: 3D structure, binding sites…
- PDB
- 1U4E
- Type
- protein
- Length
- 200 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- G protein-activated inward rectifier potassium channel 1
- UniProt
- P63250, P35562
- Pockets
- 1 · best druggability 0.29
Structure
x-ray diffraction · 1 distinct chain · 8% helix, 47% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | G protein-activated inward rectifier potassium channel 1 | protein | 200 | 8% helix, 47% strand | P63250, P35562 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 65 | 0.29 | 0.74 | 20 | empty |
Compared structures
- 1U4E · Crystal Structure of Cytoplasmic Domains of GIRK1 channel · the same entry in another collection · chain A against A, TM-score 1.00
- P63250 · AlphaFold monomer V2.0 prediction for G protein-activated inward rectifier potassium… · a predicted model of the same protein · chain A against A, TM-score 0.88
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P63250
- Every structure of UniProt P35562
- Elsewhere: RCSB PDB 1U4E · PDBe 1U4E · UniProt P63250 · UniProt P35562
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