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HASIC1A co-crystallized with nafamostat

Analyse HASIC1A co-crystallized with nafamostat in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6L6N
Type: protein
Length: 1,209 residues
Chains: 3
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P78348
Ligands: NAG, NDG, CL

Structure

x-ray diffraction · 3 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	405	—	P78348
B	—	protein	403	—	P78348
C	—	protein	401	—	P78348

Ligands and binding sites

NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 4 copies · chains A, B, C
NDG · 2-acetamido-2-deoxy-alpha-D-glucopyranose · sugar · chains A
CL · Chloride ion · ion · 2 copies · chains B, C
EDO · 1,2-ethanediol · additive · chains B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6L6N · hASIC1a co-crystallized with Nafamostat · the same entry in another collection · chain A against A, TM-score 1.00
P78348 · AlphaFold monomer V2.0 prediction for acid-sensing ion channel 1 (P78348) · a predicted model of the same protein · chain C against A, TM-score 0.95

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P78348
Elsewhere: RCSB PDB 6L6N · PDBe 6L6N · UniProt P78348

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