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Crystal structure of ATG18 from saccharomyces cerevisiae
Analyse Crystal structure of ATG18 from saccharomyces cerevisiae in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6KYB
- Type
- protein
- Length
- 1,304 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Autophagy-related protein 18
- UniProt
- P43601
- Pockets
- 20 · best druggability 0.80
Structure
x-ray diffraction · 4 distinct chains · 0% helix, 49% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Autophagy-related protein 18 | protein | 329 | 0% helix, 52% strand | P43601 |
| B | Autophagy-related protein 18 | protein | 330 | 0% helix, 55% strand | P43601 |
| C | Autophagy-related protein 18 | protein | 328 | 0% helix, 51% strand | P43601 |
| D | Autophagy-related protein 18 | protein | 317 | 0% helix, 38% strand | P43601 |
Pockets
20 pockets found on a 1 Å grid, 9 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 152 | 0.80 | 0.97 | 34 | empty |
| 2 | 695 | 0.80 | 0.84 | 57 | empty |
| 3 | 690 | 0.80 | 0.84 | 55 | empty |
| 4 | 1064 | 0.80 | 0.81 | 89 | empty |
| 5 | 735 | 0.79 | 0.83 | 58 | empty |
Interfaces
2 interfaces between chains.
- B–C · 822 Ų buried · 12 hydrogen bonds · protein-protein
- A–B · 814 Ų buried · 13 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P43601
- Elsewhere: RCSB PDB 6KYB · PDBe 6KYB · UniProt P43601
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