UniProt P43601

Autophagy-related protein 18 (P43601)

Autophagy-related protein 18 (UniProt P43601): 4 experimental structures and 1 predicted model on GenesisL1, 33 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt: P43601
Protein: Autophagy-related protein 18
Experimental structures: 4
Predicted models: 1
Pockets: 33 · 2 records with a druggable one

Structures

5 records of P43601 in the MolNFT archive: 4 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
6KYB	Crystal structure of Atg18 from Saccharomyces cerevisiae	x-ray diffraction	A, B, C, D	—	—
6KYB	Crystal structure of ATG18 from saccharomyces cerevisiae	x-ray diffraction	A, B, C, D	—	—
8AFW	Tube assembly of Atg18-WT	electron microscopy	A, B, C, D	—	13 (best 0.82)
8AFY	Subtomogram average of membrane-bound Atg18 oligomers	electron microscopy	A, B, C, D, E, F, G, H	—	20 (best 0.80)
P43601	AlphaFold monomer V2.0 prediction for autophagy-related protein 18 (P43601)	predicted	A	—	—

Experiment against prediction

8AFW chain D against the predicted model P43601: TM-score 0.97, RMSD 1.32 Å
8AFW chain B against the predicted model P43601: TM-score 0.97, RMSD 1.32 Å
6KYB chain A against the predicted model P43601: TM-score 0.97, RMSD 1.35 Å
6KYB chain A against the predicted model P43601: TM-score 0.97, RMSD 1.35 Å
8AFW chain C against the predicted model P43601: TM-score 0.97, RMSD 1.35 Å
8AFY chain G against the predicted model P43601: TM-score 0.97, RMSD 1.38 Å
8AFY chain A against the predicted model P43601: TM-score 0.97, RMSD 1.38 Å
8AFY chain C against the predicted model P43601: TM-score 0.97, RMSD 1.38 Å
8AFY chain E against the predicted model P43601: TM-score 0.97, RMSD 1.38 Å
8AFW chain A against the predicted model P43601: TM-score 0.97, RMSD 1.38 Å

Elsewhere

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