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Structure of unknow protein 4

Analyse Structure of unknow protein 4 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6K9F
Type: protein
Length: 1,044 residues
Chains: 12
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Caspase recruitment domain-containing protein 8
UniProt: Q9Y2G2
Pockets: 10 · best druggability 0.77

Structure

electron microscopy · 1 distinct chain · 80% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C, D, E, F, G, H, I, J, K, L	Caspase recruitment domain-containing protein 8	protein	87	80% helix, 0% strand	Q9Y2G2

Pockets

10 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1038	0.77	0.79	157	empty
2	524	0.70	0.80	90	empty
3	417	0.64	0.78	69	empty
4	228	0.60	0.81	37	empty
5	267	0.60	0.79	52	empty

Interfaces

28 interfaces between chains.

H–J · 505 Å² buried · 5 hydrogen bonds · protein-protein
G–K · 505 Å² buried · 3 hydrogen bonds · protein-protein
D–K · 501 Å² buried · 4 hydrogen bonds · protein-protein
A–F · 498 Å² buried · 4 hydrogen bonds · protein-protein
A–B · 490 Å² buried · 3 hydrogen bonds · protein-protein

Compared structures

6K9F · Structure of unknow protein 4 · the same entry in another collection · chain L against L, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9Y2G2
Elsewhere: RCSB PDB 6K9F · PDBe 6K9F · UniProt Q9Y2G2

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