UniProt Q9Y2G2
Caspase recruitment domain-containing protein 8 (Q9Y2G2)
Caspase recruitment domain-containing protein 8 (UniProt Q9Y2G2): 10 experimental structures and 1 predicted model on GenesisL1, 29 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9Y2G2
- Protein
- Caspase recruitment domain-containing protein 8
- Experimental structures
- 10
- Predicted models
- 1
- Pockets
- 29 · 3 records with a druggable one
Structures
11 records of Q9Y2G2 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4IKM | X-ray structure of CARD8 CARD domain | x-ray diffraction | A | — | — |
| 4IKM | X-ray structure of CARD8 card domain | x-ray diffraction | A | — | — |
| 6K9F | Structure of unknow protein 4 | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L | — | 10 (best 0.77) |
| 6K9F | Structure of unknow protein 4 | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L | — | — |
| 6XKJ | Cryo-EM structure of CARD8-CARD filament | electron microscopy | C, A, B, D, E, F, G, H, I, J, K, L, M, N, O, P | — | — |
| 6XKJ | Cryo-EM structure of CARD8-card filament | electron microscopy | C, A, B, D, E, F, G, H, I, J, K, L, M, N, O, P | — | — |
| 7JKQ | Human DPP9-CARD8 complex | electron microscopy | B, C | — | 10 (best 0.84) |
| 7JKQ | Human DPP9-CARD8 complex | electron microscopy | B, C | — | — |
| 7JN7 | Human DPP9-CARD8 complex | electron microscopy | B, C | — | 9 (best 0.78) |
| 7JN7 | Human DPP9-CARD8 complex | electron microscopy | B, C | — | — |
| Q9Y2G2 | AlphaFold monomer V2.0 prediction for caspase recruitment domain- containing protein 8 (Q9Y2G2) | predicted | A | — | — |
Experiment against prediction
- 6XKJ chain E against the predicted model Q9Y2G2: TM-score 0.98, RMSD 0.44 Å
- 6XKJ chain E against the predicted model Q9Y2G2: TM-score 0.98, RMSD 0.44 Å
- 6XKJ chain L against the predicted model Q9Y2G2: TM-score 0.98, RMSD 0.44 Å
- 6XKJ chain L against the predicted model Q9Y2G2: TM-score 0.98, RMSD 0.44 Å
- 6XKJ chain C against the predicted model Q9Y2G2: TM-score 0.98, RMSD 0.44 Å
- 6XKJ chain C against the predicted model Q9Y2G2: TM-score 0.98, RMSD 0.44 Å
- 6XKJ chain H against the predicted model Q9Y2G2: TM-score 0.98, RMSD 0.44 Å
- 6XKJ chain H against the predicted model Q9Y2G2: TM-score 0.98, RMSD 0.44 Å
- 6XKJ chain A against the predicted model Q9Y2G2: TM-score 0.98, RMSD 0.44 Å
- 6XKJ chain A against the predicted model Q9Y2G2: TM-score 0.98, RMSD 0.44 Å
Elsewhere
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