Research workbench

Cryo-EM structure of glutamate dehydrogenase from thermococcus profundus

Analyse Cryo-EM structure of glutamate dehydrogenase from thermococcus profundus in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6JNA
Type: protein
Length: 419 residues
Chains: 1
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Glutamate dehydrogenase
EC: 1.4.1.3
UniProt: O74024
Pockets: 1 · best druggability 0.72

Structure

electron microscopy · 1 distinct chain · 42% helix, 16% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Glutamate dehydrogenase (EC 1.4.1.3)	protein	419	42% helix, 16% strand	O74024

Ligands and binding sites

TRS · 2-amino-2-hydroxymethyl-propane-1,3-diol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	832	0.72	0.77	67	TRS

Compared structures

6JNA · Cryo-EM structure of glutamate dehydrogenase from Thermococcus profundus · the same entry in another collection · chain A against A, TM-score 1.00
O74024 · AlphaFold monomer V2.0 prediction for glutamate dehydrogenase (O74024) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O74024
Elsewhere: RCSB PDB 6JNA · PDBe 6JNA · UniProt O74024

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.