Research workbench
Crystal structure of kibra and angiomotin complex
Analyse Crystal structure of kibra and angiomotin complex in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6JJX
- Type
- protein
- Length
- 276 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Protein kibra; Peptide from angiomotin
- UniProt
- Q5SXA9, Q4VCS5
- Pockets
- 2 · best druggability 0.43
Structure
x-ray diffraction · 4 distinct chains · 31% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Protein kibra | protein | 118 | 31% helix, 24% strand | Q5SXA9 |
| B | Protein kibra | protein | 127 | 39% helix, 22% strand | Q5SXA9 |
| D | Peptide from angiomotin | protein | 16 | 0% helix, 0% strand | Q4VCS5 |
| C | Peptide from angiomotin | protein | 15 | 0% helix, 0% strand | Q4VCS5 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 173 | 0.43 | 0.73 | 27 | empty |
| 2 | 69 | 0.27 | 0.72 | 14 | empty |
Interfaces
3 interfaces between chains.
- A–B · 1356 Ų buried · 13 hydrogen bonds · protein-protein
- B–D · 536 Ų buried · 7 hydrogen bonds · protein-protein
- A–C · 401 Ų buried · 7 hydrogen bonds · protein-protein
Compared structures
- 6JJX · Crystal Structure of KIBRA and Angiomotin complex · the same entry in another collection · chain C against C, TM-score 1.00
- Q5SXA9 · AlphaFold monomer V2.0 prediction for protein kibra (Q5SXA9) · a predicted model of the same protein · chain A against A, TM-score 0.91
- Q4VCS5 · AlphaFold monomer V2.0 prediction for angiomotin (Q4VCS5) · a predicted model of the same protein · chain C against A, TM-score 0.33
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5SXA9
- Every structure of UniProt Q4VCS5
- Elsewhere: RCSB PDB 6JJX · PDBe 6JJX · UniProt Q5SXA9 · UniProt Q4VCS5
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