Research workbench
Human H-ferritin mutant-C90A/C102A/C130A/D144C
Analyse Human H-ferritin mutant-C90A/C102A/C130A/D144C in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6J7G
- Type
- protein
- Length
- 3,984 residues
- Chains
- 24
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ferritin heavy chain
- EC
- 1.16.3.1
- UniProt
- P02794
- Pockets
- 20 · best druggability 0.79
Structure
x-ray diffraction · 1 distinct chain · 59% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, G, H, I, J, M, N, O, P, Q, R, S, T, W, X, Y, Z, a, b, e, f | Ferritin heavy chain (EC 1.16.3.1) | protein | 166 | 59% helix, 1% strand | P02794 |
Pockets
20 pockets found on a 1 Å grid, 20 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 113 | 0.79 | 0.98 | 17 | empty |
| 2 | 108 | 0.79 | 0.98 | 21 | empty |
| 3 | 90 | 0.78 | 0.99 | 15 | empty |
| 4 | 91 | 0.78 | 0.99 | 18 | empty |
| 5 | 77 | 0.77 | 0.99 | 16 | empty |
Interfaces
72 interfaces between chains.
- A–B · 1641 Ų buried · 36 hydrogen bonds · protein-protein
- C–D · 1638 Ų buried · 24 hydrogen bonds · protein-protein
- a–b · 1619 Ų buried · 26 hydrogen bonds · protein-protein
- S–T · 1618 Ų buried · 24 hydrogen bonds · protein-protein
- Q–R · 1616 Ų buried · 42 hydrogen bonds · protein-protein
Compared structures
- 6J7G · Human H-ferritin mutant-C90A/C102A/C130A/D144C · the same entry in another collection · chain O against O, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P02794
- Elsewhere: RCSB PDB 6J7G · PDBe 6J7G · UniProt P02794
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