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D34 region of human ankyrin-R and linker

Analyse D34 region of human ankyrin-R and linker in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1N11
Type: protein
Length: 404 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Ankyrin
UniProt: P16157
Ligands: CL, BR
Pockets: 3 · best druggability 0.43

Structure

x-ray diffraction · 1 distinct chain · 50% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Ankyrin	protein	404	50% helix, 0% strand	P16157

Ligands and binding sites

CL · Chloride ion · ion · 9 copies · chains A
BR · Bromide ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	152	0.43	0.75	23	empty
2	86	0.38	0.76	20	empty
3	69	0.34	0.76	17	empty

Compared structures

1N11 · D34 region of human ankyrin-R and linker · the same entry in another collection · chain A against A, TM-score 1.00
P16157 · AlphaFold monomer V2.0 prediction for ankyrin-1 (P16157) · a predicted model of the same protein · chain A against A, TM-score 0.94

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P16157
Elsewhere: RCSB PDB 1N11 · PDBe 1N11 · UniProt P16157

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