UniProt P16157
Ankyrin-1 (P16157)
Ankyrin-1 (UniProt P16157): 30 experimental structures and 1 predicted model on GenesisL1, 9 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P16157
- Protein
- Ankyrin-1
- Experimental structures
- 30
- Predicted models
- 1
- Pockets
- 9 · 2 records with a druggable one
Structures
31 records of P16157 in the MolNFT archive: 30 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1N11 | D34 region of human ankyrin-R and linker | x-ray diffraction | A | — | — |
| 1N11 | D34 region of human ankyrin-R and linker | x-ray diffraction | A | — | — |
| 2YQF | Solution structure of the death domain of Ankyrin-1 | solution nmr | A | — | — |
| 2YQF | Solution structure of the death domain of ankyrin-1 | solution nmr | A | — | — |
| 2YVI | Crystal structure of a death domain of human ankryn protein | x-ray diffraction | A | — | — |
| 2YVI | Crystal structure of a death domain of human ankryn protein | x-ray diffraction | A | — | — |
| 3F59 | Crystal structure of ZU5-ANK, the spectrin binding region of human erythroid ankyrin | x-ray diffraction | A, B, C, D | — | — |
| 3F59 | Crystal structure of ZU5-ank, the spectrin binding region of human erythroid ankyrin | x-ray diffraction | A, B, C, D | — | — |
| 3KBT | Crystal structure of the ankyrin binding domain of human erythroid beta spectrin (repeats 13-15) in… | x-ray diffraction | C, D | — | — |
| 3KBT | Crystal structure of the ankyrin binding domain of human erythroid beta spectrin (repeats 13-15) in… | x-ray diffraction | C, D | — | — |
| 3KBU | Crystal structure of the ankyrin binding domain of human erythroid beta spectrin (repeats 13-15) in… | x-ray diffraction | C, D | — | — |
| 3KBU | Crystal structure of the ankyrin binding domain of human erythroid beta spectrin (repeats 13-15) in… | x-ray diffraction | C, D | — | — |
| 3UD1 | Crystal structure of ZU5A-ZU5B domains of human erythrocyte ankyrin | x-ray diffraction | A, B, C | — | — |
| 3UD1 | Crystal structure of ZU5A-ZU5B domains of human erythrocyte ankyrin | x-ray diffraction | A, B, C | — | — |
| 3UD2 | Crystal structure of Selenomethionine ZU5A-ZU5B protein domains of human erythrocyte ankyrin | x-ray diffraction | C, B, A | — | — |
| 3UD2 | Crystal structure of selenomethionine ZU5A-ZU5B protein domains of human erythrocyte ankyrin | x-ray diffraction | C, B, A | — | — |
| 7TW3 | Cryo-EM structure of human ankyrin complex (B2P1A1) from red blood cell | electron microscopy | G | — | — |
| 7TW5 | Cryo-EM structure of human ankyrin complex (B2P1A2) from red blood cell | electron microscopy | G, H | — | — |
| 7TW6 | Cryo-EM structure of human ankyrin complex (B4P1A1) from red blood cell | electron microscopy | G | — | — |
| 7UZQ | Local refinement of RhAG-RhCE-ANK1(AR1-5), from consensus refinement of all classes | electron microscopy | J | — | 3 (best 0.71) |
| 7UZQ | Local refinement of rhag-rhce-ANK1(AR1-5), from consensus refinement of all classes | electron microscopy | J | — | — |
| 7UZU | Ankyrin-1 (N-terminal region of membrane binding domain, local refinement from consensus… | electron microscopy | A | — | — |
| 7V0M | Local refinement of ankyrin-1 (N-terminal half), class 1 of erythrocyte ankyrin-1 complex | electron microscopy | A | — | — |
| 7V0S | Local refinement of RHAG/CE trimer, class 1 of erythrocyte ankyrin-1 complex | electron microscopy | J | — | — |
| 7V0X | Local refinement of ankyrin-1 (C-terminal half), class 1 of erythrocyte ankyrin-1 complex | electron microscopy | J | — | 1 (best 0.31) |
| 7V0X | Local refinement of ankyrin-1 (C-terminal half), class 1 of erythrocyte ankyrin-1 complex | electron microscopy | J | — | — |
| 8CS9 | Composite reconstruction of Class 1 of the erythrocyte ankyrin-1 complex | electron microscopy | A | — | 5 (best 0.79) |
| 8CSV | Local refinement of Anykyrin-1 (N-terminal half of membrane binding domain) in Class 2 of… | electron microscopy | A | — | — |
| 8CSV | Local refinement of anykyrin-1 (N-terminal half of membrane binding domain) in class 2 of… | electron microscopy | A | — | — |
| 8CTE | Class 2 of erythrocyte ankyrin-1 complex (composite MAP) | electron microscopy | A | — | — |
| P16157 | AlphaFold monomer V2.0 prediction for ankyrin-1 (P16157) | predicted | A | — | — |
Experiment against prediction
- 7UZQ chain J against the predicted model P16157: TM-score 0.99, RMSD 0.39 Å
- 7UZQ chain J against the predicted model P16157: TM-score 0.99, RMSD 0.39 Å
- 7V0S chain J against the predicted model P16157: TM-score 0.99, RMSD 0.42 Å
- 7V0X chain J against the predicted model P16157: TM-score 0.98, RMSD 1.03 Å
- 7V0X chain J against the predicted model P16157: TM-score 0.98, RMSD 1.03 Å
- 1N11 chain A against the predicted model P16157: TM-score 0.94, RMSD 1.95 Å
- 1N11 chain A against the predicted model P16157: TM-score 0.94, RMSD 1.95 Å
- 2YVI chain A against the predicted model P16157: TM-score 0.93, RMSD 1.35 Å
- 2YVI chain A against the predicted model P16157: TM-score 0.93, RMSD 1.35 Å
- 3F59 chain B against the predicted model P16157: TM-score 0.92, RMSD 1.42 Å
Elsewhere
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