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Ksga from bacillus subtilis 168

Analyse Ksga from bacillus subtilis 168 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6IFS
Type: protein
Length: 567 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Ribosomal RNA small subunit methyltransferase a
EC: 2.1.1.182
UniProt: P37468
Pockets: 4 · best druggability 0.73

Structure

x-ray diffraction · 2 distinct chains · 44% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Ribosomal RNA small subunit methyltransferase a (EC 2.1.1.182)	protein	290	44% helix, 18% strand	P37468
B	Ribosomal RNA small subunit methyltransferase a (EC 2.1.1.182)	protein	277	43% helix, 19% strand	P37468

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	808	0.73	0.78	90	empty
2	311	0.69	0.83	45	empty
3	102	0.36	0.74	19	empty
4	78	0.34	0.75	14	empty

Interfaces

1 interface between chains.

A–B · 369 Å² buried · 6 hydrogen bonds · protein-protein

Compared structures

6IFS · KsgA from Bacillus subtilis 168 · the same entry in another collection · chain A against A, TM-score 1.00
P37468 · AlphaFold monomer V2.0 prediction for ribosomal RNA small subunit methyltransferase a… · a predicted model of the same protein · chain B against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P37468
Elsewhere: RCSB PDB 6IFS · PDBe 6IFS · UniProt P37468

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