Research workbench
Structure of the catalytic domain of USP28 (insertion deleted)
Analyse Structure of the catalytic domain of USP28 (insertion deleted) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6HEH
- Type
- protein
- Length
- 339 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ubiquitin carboxyl-terminal hydrolase 28,UBIQUITIN carboxyl-terminal hydrolase 28
- EC
- 3.4.19.12
- UniProt
- Q96RU2
- Ligands
- CL
- Pockets
- 3 · best druggability 0.62
Structure
x-ray diffraction · 1 distinct chain · 41% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ubiquitin carboxyl-terminal hydrolase 28,UBIQUITIN carboxyl-terminal hydrolase 28 (EC 3.4.19.12) | protein | 339 | 41% helix, 24% strand | Q96RU2 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 153 | 0.62 | 0.84 | 33 | empty |
| 2 | 162 | 0.50 | 0.78 | 29 | empty |
| 3 | 88 | 0.38 | 0.76 | 20 | empty |
Compared structures
- 6HEH · Structure of the catalytic domain of USP28 (insertion deleted) · the same entry in another collection · chain A against A, TM-score 1.00
- Q96RU2 · AlphaFold monomer V2.0 prediction for ubiquitin carboxyl-terminal hydrolase 28 (Q96RU2) · a predicted model of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q96RU2
- Elsewhere: RCSB PDB 6HEH · PDBe 6HEH · UniProt Q96RU2
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.