Research workbench
Structure of the human GABARAPL2 protein in complex with the UBA5 lir motif
Analyse Structure of the human GABARAPL2 protein in complex with the UBA5 lir motif in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6H8C
- Type
- protein
- Length
- 135 residues
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Gamma-aminobutyric acid receptor-associated protein-like 2; Ubiquitin-like…
- UniProt
- P60520, Q9GZZ9
- Pockets
- 1 · best druggability 0.35
Structure
solution nmr · 2 distinct chains · 29% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Gamma-aminobutyric acid receptor-associated protein-like 2 | protein | 116 | 34% helix, 23% strand | P60520 |
| B | Ubiquitin-like modifier-activating enzyme 5 | protein | 19 | 0% helix, 21% strand | Q9GZZ9 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 79 | 0.35 | 0.75 | 13 | empty |
Interfaces
1 interface between chains.
- A–B · 1022 Ų buried · 18 hydrogen bonds · protein-protein
Compared structures
- 6H8C · Structure of the human GABARAPL2 protein in complex with the UBA5 LIR motif · the same entry in another collection · chain A against A, TM-score 1.00
- P60520 · AlphaFold monomer V2.0 prediction for gamma-aminobutyric acid receptor-associated… · a predicted model of the same protein · chain A against A, TM-score 0.89
- Q9GZZ9 · AlphaFold monomer V2.0 prediction for ubiquitin-like modifier- activating enzyme 5… · a predicted model of the same protein · chain B against A, TM-score 0.23
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P60520
- Every structure of UniProt Q9GZZ9
- Elsewhere: RCSB PDB 6H8C · PDBe 6H8C · UniProt P60520 · UniProt Q9GZZ9
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