Crystal structure of KDM4D with tetrazolylhydrazide ligand NS035

Structure

x-ray diffraction · 1 distinct chain.

Ligands and binding sites

• FHW · (2~{R})-3-phenyl-2-(2~{H}-1,2,3,4-tetrazol-5-yl) propanehydrazide · ligand · chains A
• I1L · [2-(2~{H}-1,2,3,4-tetrazol-5-yl)ethanoylamino]azanium · ligand · chains A
• ZN · Zinc ion · metal · chains A
• NA · Sodium ion · metal · chains A
• NI · Nickel (II) ion · metal · chains A
• SO4 · Sulfate ion · ion · chains A
• CL · Chloride ion · ion · chains A
• EDO · 1,2-ethanediol · additive · 9 copies · chains A
• EPE · 4-(2-hydroxyethyl)-1-piperazine ethanesulfonic acid · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

• 6H0W · Crystal Structure of KDM4D with tetrazolylhydrazide ligand NS035 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt Q6B0I6
• Elsewhere: RCSB PDB 6H0W · PDBe 6H0W · UniProt Q6B0I6