Research workbench
Human aurkc incenp complex bound to brd-7880
Analyse Human aurkc incenp complex bound to brd-7880 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6GR8
- Type
- protein
- Length
- 338 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q9UQB9, Q9NQS7
- Ligands
- F8Z
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 272 | — | Q9UQB9 |
| B | — | protein | 66 | — | Q9NQS7 |
Ligands and binding sites
- F8Z · 1-[(2~{R},3~{S})-2-[[1,3-benzodioxol-5-ylmethyl(methyl)amino]methyl]-3-methyl-6-oxidanylidene-5-[(2~{S})-1-oxidanylpropan-2-yl]-3,4-dihydro-2~{H}-1,5-benzoxazocin-8-yl]-3-(4-methoxyphenyl)urea · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6GR8 · Human AURKC INCENP complex bound to BRD-7880 · the same entry in another collection · chain A against A, TM-score 1.00
- Q9UQB9 · AlphaFold monomer V2.0 prediction for aurora kinase C (Q9UQB9) · a predicted model of the same protein · chain A against A, TM-score 0.97
- Q9NQS7 · AlphaFold monomer V2.0 prediction for inner centromere protein (Q9NQS7) · a predicted model of the same protein · chain B against A, TM-score 0.50
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9UQB9
- Every structure of UniProt Q9NQS7
- Elsewhere: RCSB PDB 6GR8 · PDBe 6GR8 · UniProt Q9UQB9 · UniProt Q9NQS7
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