UniProt Q9UQB9
Q9UQB9
Q9UQB9 (UniProt Q9UQB9): 3 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9UQB9
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 3
Structures
4 records of Q9UQB9 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6GR8 | Human aurkc incenp complex bound to brd-7880 | x-ray diffraction | A | F8Z | — |
| 6GR9 | Human AURKC INCENP complex bound to VX-680 | x-ray diffraction | A | VX6, SO4 | — |
| 6GR9 | Human aurkc incenp complex bound to vx-680 | x-ray diffraction | A | VX6, SO4 | — |
| Q9UQB9 | AlphaFold monomer V2.0 prediction for aurora kinase C (Q9UQB9) | predicted | A | — | — |
Ligands
- SO4 · Sulfate ion · in 2 records
- VX6 · Cyclopropanecarboxylic acid {4-[4-(4-methyl-piperazin-1-yl)-6-(5-methyl-2H-pyrazol-3-ylamino)-pyrimidin-2-ylsulfanyl]-phenyl}-amide · in 2 records
- F8Z · 1-[(2~{R},3~{S})-2-[[1,3-benzodioxol-5-ylmethyl(methyl)amino]methyl]-3-methyl-6-oxidanylidene-5-[(2~{S})-1-oxidanylpropan-2-yl]-3,4-dihydro-2~{H}-1,5-benzoxazocin-8-yl]-3-(4-methoxyphenyl)urea · in 1 record
Experiment against prediction
- 6GR9 chain A against the predicted model Q9UQB9: TM-score 0.98, RMSD 0.96 Å
- 6GR9 chain A against the predicted model Q9UQB9: TM-score 0.98, RMSD 0.96 Å
- 6GR8 chain A against the predicted model Q9UQB9: TM-score 0.97, RMSD 1.19 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.